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Kisspeptin lab report: what to check on a Kisspeptin COA
Kisspeptin is a short synthetic peptide: ten amino acids, with an amide at the end of the chain. Its lab report answers the same three questions as any other (how pure, what it is, how much), and a few details are worth knowing before you read it: the small changes the chain can go through in storage, and the amide at the end of the chain. This guide covers what a Kisspeptin certificate of analysis (COA) should show and walks through our own report. For the basics of any report, see How to read a peptide lab report.
The short version
What Kisspeptin is, chemically
Our Kisspeptin is the 10 amino acid form: tyrosine, asparagine, tryptophan, asparagine, serine, phenylalanine, glycine, leucine, arginine and phenylalanine, written YNWNSFGLRF from their one letter codes. The last amino acid carries an amide (NH2) in place of the usual acid group. It is the shortest member of the kisspeptin family of peptides, which all share the same last ten amino acids. Lab reports often call this form Kisspeptin-10, and ours does.
| Reference fact | Kisspeptin, as on our product page |
|---|---|
| Sequence | Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2 |
| One letter code | YNWNSFGLRF-NH2 |
| Form | Freeze dried (lyophilized) powder, 10mg vials |
Purity: what the small peaks would be
Purity comes from HPLC with a UV detector: the sample runs through a column, and each component draws its own peak. Purity is the Kisspeptin peak as a share of every peak the detector picks up. With a tryptophan, a tyrosine and two phenylalanines in its chain, Kisspeptin absorbs ultraviolet light well and gives a clear signal.
On a Kisspeptin report, the small peaks worth knowing are:
- Near copies from synthesis, such as a chain missing one amino acid. They come off the column close to the main peak, so a good method keeps them separate from it.
- Deamidated forms. Each of the two asparagines can slowly lose the amide group on its side chain in moisture and warmth.
- Oxidized tryptophan. The tryptophan can take up an oxygen atom with air, light or heat.
Keeping the powder sealed, cold, dry and dark keeps these small: our product page lists minus 20 °C or colder, away from light and moisture. Our report gives a purity of 99.08%. For how purity differs from the amount in the vial, see Purity vs content.
Identity: what mass spec confirms
Mass spectrometry confirms the main peak is Kisspeptin by weighing it. The report should state that the measured mass matches Kisspeptin, the compound named on it. Mass spec also tells the amide form apart from the free acid, and the 10 amino acid form apart from the longer kisspeptins.
Our report used ESI-QTOF, a high resolution kind of mass spectrometer, and lists the identity result as Conforms. The one page we link does not print the spectrum or the measured masses.
Content: above the label on our report
Content is the milligrams of Kisspeptin the lab measured in the vial. It is not the same as purity, and not the same as the powder as a whole, which also holds salts and a little water. Our report measured it per vial: 13.79 mg, which it gives as 137.9% of the 10 mg on the label. That is above the label, not below. Like every report, it describes the one vial that was tested, so other vials can land above or below that.
Our Kisspeptin report
Our Kisspeptin is listed with a report from Premier Analytical Sciences, an independent lab in Mission Hills, California: report PAS-2026-9628, issued September 29, 2026. It covers one numbered 10 mg vial (lab number PAS-26-00281), received intact and sealed on September 24 and analyzed on September 29. The report names the material Kisspeptin-10 and shows two photos of the vial: as received, and with the lab number on it.
| On the report | Our report | Check against |
|---|---|---|
| Purity | 99.08% | 98% or higher |
| Content | 13.79 mg (137.9% of label) | The 10mg label |
| Identity | Conforms | The compound named on the report |
All three results were measured by HPLC with UV detection and ESI-QTOF mass spectrometry; the methods note cites the USP chapter on chromatography (621) and the lab’s SOP-13. The report says its results relate only to the sample tested, and our product page says when the current lot isn’t confirmed as that sample.
Checking a Kisspeptin report, step by step
- Name and sequence: Kisspeptin (or Kisspeptin-10), YNWNSFGLRF-NH2.
- Purity from HPLC, 98% or higher, with no large second peak close to the main one.
- Identity from mass spec: the report states that the measured mass matches Kisspeptin (ours: Conforms).
- Content in milligrams, close to or above the 10mg on the label.
- The lab and report number on the report, PAS-2026-9628 for ours, matching the product page.
Common questions
Is Kisspeptin the same as Kisspeptin-10?
On our site, yes: Kisspeptin is the 10 amino acid form, which our report calls Kisspeptin-10. Longer forms of 13, 14 and 54 amino acids end in the same ten amino acids, but each is a different molecule, and mass spec tells them apart.
What does Conforms mean on the report?
It is the lab’s identity result: what it measured matched the material named on the report.
Where do I find the Kisspeptin report?
On the Kisspeptin product page under Specifications & documentation, and on our research materials page, which lists every report.