NAD+

NAD+ is a coenzyme involved in cellular redox chemistry and enzyme reactions. Its research value comes from two distinct roles: participating in electron transfer and serving as a substrate for enzymes that modify other molecules.

About NAD+

The “+” identifies the oxidized form, which is paired with reduced NADH. Conversion between the two accompanies many metabolic reactions, so their relative amounts tell researchers something different from the total NAD pool. Studies using cellular biosensors examine that redox balance across metabolic conditions and within distinct cellular compartments.

NAD+ also participates directly in protein-deacetylation reactions catalyzed by members of the sirtuin family. These enzymes remove acetyl groups from proteins. In this setting, NAD+ is consumed as part of the reaction instead of simply cycling between its oxidized and reduced forms.

Because NAD+ participates in both kinds of reaction, its availability sits at the intersection of metabolism and protein regulation. The balance between NAD+ and NADH describes redox state, while NAD-dependent enzyme activity reveals another aspect of how the coenzyme is being used.

Research focus

• NAD+/NADH balance in metabolic systems.
• NAD-dependent enzyme reactions.
• Cellular and subcellular redox measurement.

Quality, Purity and Documentation

Review the analytical documentation listed for the selected size. Reports describe the samples identified in them; they do not by themselves confirm that current stock matches those samples. If no matching report is listed, contact Prestige Peptides for documentation before ordering.

Available sizes

NAD+ is supplied as a lyophilized (freeze-dried) powder in sealed vials in 500mg and 1000mg formats. Lyophilization removes water under vacuum at low temperature, producing a stable dry preparation suited to controlled laboratory storage and accurate gravimetric preparation of experimental solutions.

Storage and handling

Store lyophilized vials at -20°C or below, protected from light and moisture. Allow sealed vials to equilibrate to room temperature before opening to limit condensation inside the vial. Once opened, handle with clean laboratory technique, minimize exposure to ambient humidity, reseal promptly, and record the lot number in laboratory documentation for traceability.

For qualified in-vitro laboratory research only. Not for human or animal use.